Microsoft doesn't make this easy. For exactly the same price (ā¬30.40 per user per month) they sell two versions of Copilot: one running on Microsoft 365 Business licences, and one running on Microsoft 365 Enterprise (E3/E5). Sounds the same, isn't. The Enterprise version has extra functionality that for compliance-sensitive sectors can be critical ā and that you simply don't get in the Business version.
For SMBs the choice isn't as straightforward as Microsoft suggests. Below we explain the difference concretely, with a decision table by SMB size and industry.
The two versions in one sentence
- Copilot for Microsoft 365 Business: AI assistant in Word/Excel/Outlook/PowerPoint/Teams for M365 Business Standard/Premium licences. Available from 1 user.
- Copilot for Microsoft 365 Enterprise: same AI assistant but tied to E3/E5 licences, with additional compliance and security features (sensitivity labels, advanced data governance, customer-managed keys, and in some tiers per-user data isolation).
Both cost ā¬30.40 per user per month on top of the underlying M365 licence. The licence you buy Copilot with determines what you get ā not the Copilot licence itself.
Where the real difference sits
1. Sensitivity labels and DLP
Copilot can, if set up right, NOT show information to an employee they don't have access to. The problem is that many SMBs never set up M365 permissions properly ā everything lives in one big SharePoint where everyone has access.
In Business sensitivity labels are limited: you can apply labels, but no rule-based auto-labelling, no mandatory labelling on new documents and no integration with Microsoft Purview for data classification.
In Enterprise (E3/E5) you get the full sensitivity-labels system including auto-classification based on content, mandatory labelling, and DLP-policy integration. For a law firm that must keep dossiers strictly separated or a healthcare institution with patient data this isn't optional ā it's required.
2. Customer-managed encryption keys
In Business, your data is encrypted with keys Microsoft manages. In E5 with the right compliance add-on you can bring your own keys (BYOK) or even keys in Azure Key Vault.
3. Per-user audit logs for Copilot
Who asked Copilot which question, and what answer did they receive? In Business: limited audit trail. In E5: full audit log via Microsoft Purview Audit (Premium), including long-term retention up to 10 years.
Decision table by SMB size
| Type of company | Recommendation |
|---|---|
| 5-25 staff, no compliance | Business + Copilot |
| 5-25 staff, healthcare or legal | E3 + Copilot (sensitivity labels needed) |
| 25-100 staff, no compliance | Business usually sufficient |
| 25-100 staff, NIS2-relevant | E3 + Copilot |
| 100+ staff | E3 or E5 + Copilot |
What we usually advise
For SMBs without strict compliance: stay on Business + Copilot. Saves ā¬500/mo for 20 staff vs E3 + Copilot, with marginal added value for most organisations.
For healthcare, legal and compliance-sensitive finance: go straight to E3 + Copilot. Sensitivity labels and audit logs aren't a luxury but a hygiene requirement.
For doubt cases: we can review your situation in one conversation. We don't sell licences ā we advise what fits and set it up neatly for you. Book a licence review.
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